Sexually transmitted infections

Sexually transmitted infections are most often present without any symptom at all — which prevents neither transmission nor complications.

Illustration: Sexually transmitted infections

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The essentials in a few lines

A sexually transmitted infection can be present without producing the slightest symptom: that is the most common situation, and it is why these infections circulate. Three habits cover most of the risk. Condoms, including for oral and anal sex, remain the only protection that works against nearly all of them. Regular testing, at every change of partner and before stopping condoms in a new relationship, is the only way to detect what cannot be seen. And vaccines exist against three of them: those against HPV and hepatitis B are highly effective (WHO, 2025), and the mpox vaccine is recommended for people at risk (WHO, 2024).

Everything else depends on the infection: how long after exposure a test becomes reliable, which sample to ask for, how long treatment lasts and what complications are possible vary a great deal. Each page below sets out those details.

The infections, one by one

Twelve detailed pages: what the infection is, how it is transmitted, which signs should prompt a check, which test to ask for and when, what treatment involves, what happens without it, and what to do after a diagnosis.

True or false: what you think you know about STIs

Ten statements to judge, each corrected with a link to the right page.

Which test, and when?

The real question is not which test but when: a test taken too early says nothing. A few questions, and you will know what to ask for, and when.

Chlamydia

The most common in under-25s, and the quietest: no symptoms in about half of cases.

Gonorrhoea

Rising sharply and increasingly resistant to antibiotics; almost always silent in the throat.

Syphilis

Moves in stages separated by long silent periods; curable with a single injection.

HPV

The most widespread infection in the world: usually cleared unaided, sometimes a cause of cancer.

Genital herpes

A lifelong but usually mild infection; transmission mostly happens with nothing visible.

Hepatitis B

Spread through sex and blood, preventable by vaccine, sometimes chronic.

Hepatitis C

Mainly blood-borne; cured in eight to twelve weeks since direct-acting antivirals arrived.

HIV and AIDS

Cannot be cured but is fully controlled: on effective treatment the virus is not transmitted.

Trichomoniasis

The most common curable STI worldwide, almost always silent in men.

Mycoplasma genitalium

A frequent cause of persistent urethritis, already heavily macrolide-resistant.

Pubic lice and scabies

Two ordinary parasites, easily treated — provided the household is treated too.

Mpox

Passed on through close contact during sex; preventable by vaccination.

Symptoms that warrant a check

Unusual discharge, burning on passing urine, persistent itching, a sore, spot or wart on the genitals or around the anus, pain during sex, unusual bleeding, tender glands: all of these justify a prompt appointment. But the absence of symptoms rules nothing out — most infections produce none, and someone who feels perfectly well can be infectious.

When to test

Once a diagnosis is made

Notifying recent partners is the single most effective step, for them and for you: without it, reinfection is the rule rather than the exception. Most services will do it on your behalf, anonymously, if the conversation is difficult. A diagnosis should also prompt a full screen: these infections rarely travel alone.

After a risky encounter

Following a recent exposure carrying a significant risk of HIV transmission, post-exposure treatment can be prescribed by emergency services. It must begin as early as possible, ideally within four hours, and is no longer offered beyond 48 to 72 hours. That deadline is the only thing that matters: do not leave it until tomorrow.

Who to see for this problem?

The page Who to see, and when gives, symptom by symptom, the right professional — family doctor, urologist, gynaecologist, sex therapist, psychologist — and the emergencies that cannot wait.

What about you?

Your last STI test was…

Anonymous vote, no account: results appear after you vote, for all readers, readers of the English site and readers in your country. All the results: the polls page.

Sources

  1. Sexually transmitted infections (STIs) — World Health Organization (WHO), 2025: STIs most often asymptomatic, condom effectiveness, safe and effective vaccines against hepatitis B and papillomaviruses
  2. Mpox — World Health Organization (WHO), 2024: mpox transmitted through close contact, including sexual contact, and existence of recommended vaccines for exposed people
  3. Hepatitis B — World Health Organization (WHO), 2026: sexual transmission of hepatitis B, and a safe and effective vaccine offering almost complete protection
  4. Chlamydial Infections - STI Treatment Guidelines — Centers for Disease Control and Prevention (CDC), 2021: partners of the last 60 days and the last partner beyond that; retesting three months after treatment

Official or institutional documents this page relies on, consulted on 12 October 2026. Links open in a new tab.

Further reading

Links to official or reference sources. They open in a new tab.

Page checked in . The instruments cited can change: if in doubt, confirm with the official source given.

Text prepared with artificial intelligence, reviewed and checked by the AffectionPlus team (method and sources: About). This content does not replace medical or legal advice. Spotted an error? Write to us.

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