Intrauterine insemination

Placing prepared sperm directly in the uterus at the right moment. A few minutes, no anaesthetic — and one clear limit: four to six attempts.

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Who it is for

Insemination requires at least one patent tube and usable sperm. On that basis it suits mild sperm abnormalities, hostile cervical mucus, ejaculation disorders, unexplained infertility, and every project that goes through donor sperm — female couples and single women where the law allows.

The technical figure that matters is the count of motile sperm after preparation. Below one million the chances become very low and IVF is offered instead.

Step by step

A laboratory technician prepares a sperm sample next to a centrifuge and a microscope
Preparation in the laboratory, about an hour: the sperm is washed and centrifuged, keeping only the motile sperm cells in a small volume.

The numbers

10 to 15 % pregnancies per attempt under 35, around 5 % after 40. These rates accumulate: over four to six cycles a substantial share of suitable couples conceive. Beyond that the curve flattens — further attempts add almost nothing and cost time that matters.

What hurts, what does not

The procedure is rarely painful; when it is, the cervix is the cause, and a different catheter usually solves it. Light bleeding is ordinary. Fever, increasing pain or offensive discharge in the following days warrant a call: infection is rare but real.

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Common questions

Do you need to lie down afterwards?

No. Trials show no benefit beyond a few minutes of comfort. Sperm placed in the uterine cavity does not fall out.

Can you have sex the same day?

Yes, and it is if anything favourable. Nothing requires abstinence after the procedure.

How long should abstinence be before the sample?

Two to five days. Less and the count falls; much more and motility deteriorates. A week of abstinence does not build up a reserve.

Sources

  1. Intrauterine insemination (IUI) — Human Fertilisation and Embryology Authority, United Kingdom (HFEA), 2016
  2. Evidence-based guideline: unexplained infertility — academic.oup.com, 2023
  3. Risks of fertility treatment — Human Fertilisation and Embryology Authority, United Kingdom (HFEA), 2016

Official or institutional documents this page relies on, consulted on 12 October 2026. Links open in a new tab.

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Text prepared with artificial intelligence, reviewed and checked by the AffectionPlus team (method and sources: About). This content does not replace medical or legal advice. Spotted an error? Write to us.

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