Hepatitis B — South Africa

Infant vaccination since 1995, but the birth dose was added only much more recently.

Illustration: Hepatitis B — South Africa

The legal framework

South Africa introduced hepatitis B into routine infant immunisation in 1995, starting at six weeks. For many years there was no birth dose, which left transmission from mother to child inadequately addressed; a birth dose has since been introduced. Antenatal screening has historically not been universal, another difference from most comparable countries.

South Africa introduced hepatitis B into the expanded programme on immunisation in 1995, from six weeks of age, and added a universal birth dose to the schedule more recently — a significant change, since the six-week start left the perinatal window open. Prevalence is intermediate, and co-infection with HIV complicates management.

Key points

Infant vaccinationIn the routine schedule since 1995, from six weeks
Birth doseAdded only recently, after years without one
Antenatal screeningHistorically not universal; practice is changing
PrevalenceIntermediate to high, varying by province
HIV co-infectionCommon, and changes both monitoring and treatment
TreatmentAvailable in the public sector, often alongside HIV treatment
TestingAvailable at clinics; ask for it explicitly

In practice

Cost and coverage

Testing and treatment are free in the public sector.

Where to go

Worth knowing

If you are living with HIV, the antiretroviral regimen you take may already treat hepatitis B. Stopping or changing it without accounting for that can cause a dangerous flare — always mention both infections.

Frequently asked questions

Has the birth dose been added in South Africa?

Yes, a birth dose was added to the schedule to close the gap left by starting at six weeks, which is the period when mother-to-child transmission occurs. Ask that it is given and recorded in the Road to Health booklet.

Why does the birth dose matter so much?

Because transmission from mother to baby at birth is the route most likely to produce a lifelong chronic infection — an infant infected at birth has a very high chance of never clearing the virus, whereas an adult usually does. A vaccine dose within twenty-four hours of birth, with immunoglobulin where the mother is positive, prevents this in the great majority of cases.

Official sources and links

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Page checked in September 2026. The instruments cited can change: if in doubt, confirm with the official source given.

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